Eosinophilic GI Disorders (EGID) following Immunosuppression for Liver Transplantation

Immunosuppression after Liver Transplantation

Liver transplantation: immunosuppression and oncology

PURPOSE OF REVIEW Long-term survival of liver transplant recipients is threatened by increased rates of de-novo malignancy and recurrence of hepatocellular carcinoma (HCC), both events tightly related to immunosuppression. RECENT FINDINGS There is accumulating evidence linking increased exposure to immunosuppressants and carcinogenesis, particularly concerning calcineurin inhibitors (CNIs), a...

Long-term outcome following pediatric liver transplantation for metabolic disorders.

In order to determine long-term outcome, including survival, growth and development, following liver transplantation in children with metabolic disorders, we retrospectively reviewed charts of 54 children with metabolic disorders evaluated from 1989-2005 for presenting symptoms, transplantation timing and indications, survival, metabolic parameters, growth, and development. Thirty-three patient...

Recurrence of fatty liver disease following liver transplantation for NAFLD-related cirrhosis: Current status and challenges

Non-alcoholic fatty liver disease (NAFLD) is emerging as a major health problem worldwide. NAFLD is a continuum of disease ranging from mild liver steatosis to severe steatohepatitis, which will ultimately lead to end-stage liver disease with high morbidity and mortality rates. This disorder is considered as a silent liver disease. The metabolic syndrome and its components are accounted as the ...

Towards Steroid-Free Immunosuppression after Liver Transplantation

The deleterious long-term side effects and metabolic complications of corticosteroids have inspired initial clinical investigation of corticosteroid withdrawal and avoidance protocols in liver transplantation. The original studies in the 1990s focused on the safety of steroid withdrawal in patients without hepato-cellular carcinoma (HCC). 1,2 Subsequent clinical trials suggested noninferiority ...